In the Dune universe, the absence of artificial intelligence is justified by deep ethical reasons. The dialogue between Paul Atreides and Reverend Mother Gaius Helen Mohiam emphasises the prohibition against creating machines that imitate the human mind, which is considered an act of counterfeiting and degrading the human essence. This prohibition is linked to the commandment “Thou shalt not disfigure the soul” which unifies all the religions against corrupting human nature and was introduced after the Butlerian Jihad. Frank Herbert, through his characters, explores defending personal and spiritual autonomy, criticising AI addiction as a threat to human freedom and dignity.